Skin Rejuvenation

Bio-Stimulator Injections

Bio-stimulator injections, also known as collagen-stimulating injections, offer an injectable solution designed to enhance skin texture, elasticity, overall skin quality, and reduce sagging in the lower face by stimulating collagen production. Collagen, a foundational protein, provides structure and elasticity to the skin. However, as we age, our body's natural collagen production diminishes..

What Are Bio-Stimulator Injections Made Of?

Bio-stimulating fillers contain Calcium Hydroxyapatite microspheres within a gel carrier molecule. When injected into the skin, the gel carrier molecules provide immediate volume correction. Over time, the gel is absorbed, revealing the microspheres, which stimulate neo-collagenesis.

Areas Suitable for Collagen-Stimulating Injections:

Collagen-stimulating injections are versatile and can be applied to various facial regions, including the cheeks, jawline, and nasolabial folds. Furthermore, they can enhance skin texture in other body areas like the neck, décolletage, and even hands. In addition. bio-stimulator injections can also be used  to treat cellulite.

Candidates Eligibility for  Collagen-Stimulating Injections:

Ideal candidates for collagen-stimulating injections are clients who wish to improve skin texture, tone, and volume. They should be in good overall health and have realistic expectations.

Unsuitable Candidates for Collagen-Stimulating Injections:

Clients with specific medical conditions, such as autoimmune diseases, bleeding disorders, recent or current infections, or permanent facial implants in the treatment areas, may not be suitable candidates. Additionally, pregnant or breastfeeding individuals should refrain from this treatment.

Duration of Bio-Stimulator Injections:

Results from bio-stimulator injections typically last up to 12 months, with some patients opting for additional treatments at 12 to 18 months. Combining bio-stimulator injections with other cosmetic treatments, such as anti-wrinkle injections, dermal fillers, or laser facial resurfacing, is recommended for comprehensive and long-lasting results.

The Treatment Process:

Before receiving bio-stimulating injections, a consultation is necessary to assess your facial features, address concerns, and develop a personalized treatment plan. The treatment process involves cleaning the face with an antiseptic and applying local anaesthesia to numb the area. At the Marr Clinic, we prioritize patient comfort and safety by using cannulas instead of sharp needles. Treatment typically takes around 30 minutes, depending on the treated area and the quantity of syringes used.

Risks and Side Effects of Bio-Stimulator Injections:

Common side effects include swelling, bruising, temporary redness, and tenderness. Mild discomfort or pain can be managed with oral analgesics. Nodules (small lumps) may form, but massaging the treated area can prevent this. Rare instances of infection or granuloma formation can occur, and extremely rare cases of vascular occlusion are minimized with the use of cannulas.

Expected Results from Bio-Stimulator Injections:

Results can vary depending on the body's ability to produce new collagen, with full effects taking up to 6 months to manifest. Improvements may include enhanced skin texture, firmness, and increased facial volume.

How Bio-Stimulator Injections Differ from Dermal Fillers:

Bio-stimulator injections and dermal fillers, both injectable cosmetic treatments, have significant differences. Dermal fillers provide immediate results by adding volume through the hydrophilic (water-attracting) action of hyaluronic acid. In contrast, bio-stimulator injections stimulate collagen production, requiring time to reveal their full benefits. Moreover, unlike hyaluronic dermal fillers, bio-stimulators cannot be removed with Hyaluronidase. They are also less prone to causing puffiness if administered excessively, unlike dermal fillers.


Dr May Marr Cosmetic Physician Lennox Head


Dr May Marr is a Flinders University Medical School graduate and a member of the Royal Australasian College of Physicians. She has a long-held interest in aesthetic medical procedures and evidence-based skin care. She holds a passionate belief that people should have access to procedures and products that are research-backed, ethically prescribed and skilfully delivered.

Dr Marr has trained with Dr Jacque Le Coz at the Institute of Mesotherapy in Paris. She holds an Advanced Diploma in Dermatology from the Australian Institute of Dermatology and in 2020 completed her Dermatology Fellowship.

The ethical, educational and procedural standards that Dr Marr brings to aesthetic medicine have been recognised by some of the largest aesthetic companies in the world. She holds advanced injector status and her extensive clinical experience sees her regularly called upon as an industry educator.